DETOXIFICATION OF ANIMALS' LIVER WITH MODISORB PLUS WHEN EXPOSED TO HEAVY METALS

Authors

  • E. K. Rakhmatullin Federal Center for Toxicological, Radiation and Biological Safety
  • I. R. Kadikov Federal Center for Toxicological, Radiation and Biological Safety
  • E. N. Mayorova Federal Center for Toxicological, Radiation and Biological Safety
  • E. I. Kurshakova Federal Center for Toxicological, Radiation and Biological Safety
  • I. F. Vafin Federal Center for Toxicological, Radiation and Biological Safety
  • G. G. Galyautdinova Federal Center for Toxicological, Radiation and Biological Safety
  • A. A. Korchemkin Federal Center for Toxicological, Radiation and Biological Safety
  • D. R. Sagdeev Federal Center for Toxicological, Radiation and Biological Safety

DOI:

https://doi.org/10.31857/S2500208225030152

Keywords:

Modisorb plus, sheep, heavy metals, cadmium, lead, aspartate aminotransferase (AST), alanine aminotransferase (ALT), de Ritis coefficient, alkaline phosphatase (ALP), R index

Abstract

The article presents the results of a study to justify the usage of Modisorb Plus in combined toxic liver damage in animals with cadmium chloride and lead acetate. It has been established that the usage of Modisorb Plus in the diet of sheep, as a therapeutic and prophylactic agent for damage by cadmium and lead, helps to normalize hematological parameters. Adding 25 mg / kg of the drug to sheep feed contaminated with cadmium chloride and lead acetate (Group III) for 45 days helps prevent the development of pathological changes in the liver of sheep. Modisorb Plus has a hepatoprotective effect and can be recommended, as a therapeutic and prophylactic agent, when the liver of animals is exposed to cadmium and lead in ecologically unfavorable regions.

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Published

2025-06-18

Issue

No. 3 (2025): May-June

Section

ЗООТЕХНИЯ

How to Cite

Rakhmatullin, E. K., Kadikov, I. R., Mayorova, E. N., Kurshakova, E. I., Vafin, I. F., Galyautdinova, G. G., Korchemkin, A. A., & Sagdeev, D. R. (2025). DETOXIFICATION OF ANIMALS’ LIVER WITH MODISORB PLUS WHEN EXPOSED TO HEAVY METALS. Vestnik of the Russian Agricultural Science, 3, 75-78. https://doi.org/10.31857/S2500208225030152