Comparative analysis of the different-sized copper and iron nanoparticles biological effects
Keywords:
bioluminescence, iron nanoparticles, copper nanoparticles, E. coli K12TG1, Gallus gallus, AST, ALT, MDAAbstract
The studies have shown that Fe and Cu nanoparticles that differ by the production technology and main characteristics show different activity towards test objects. Comparing two models of E. coli K12TG1 and Gallus gallus, we obtained data on toxicity levels according to EC30 indicators and biological effects on broiler chickens. Experimentally we established concentration constants of nanoparticles with different sizes that determine bioluminescence quenching, which is closely associated with toxic effect of trace metals on the model of warm-blooded animals (Gallus gallus). The obtained data including nanoparticles toxicity on model E. coli K12TG1, the biological effect may be the basis for universal express tests.
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